Despite several medical advancements, resuscitation techniques, life support equipment, sepsis remains the significant cause of morbidity and mortality in hospitalized or critically sick patients. In addition, it remains the most prevalent nosocomial infection worldwide. Sepsis treatment mainly focuses on early diagnosis and timely initiation of broad-spectrum antimicrobial therapy are warranted to prevent fatal sepsis shock and increase the sepsis survival rate. Moreover, severe sepsis infection or septic shock imposes a substantial economic or financial burden on patients and healthcare systems, often requiring intensive care unit (ICU) treatment for a long duration. Besides, growing antimicrobial resistance globally has made it often more challenging to tackle sepsis infection. Accelerate sepsis research with high-quality human specimens from Central BioHub.
Signs and Symptoms of Sepsis:
Clinical diagnosis of sepsis disease is often challenging, which requires a greater index of suspicion to detect illness, especially in older people, due to its ambiguous nature. Most individuals experience an abrupt emergence of sepsis symptoms that rapidly evolve from one to another. General signs of sepsis and symptoms include sudden high-grade fever with chills, hyperventilation, thrombocytopenia, tachycardia, leukocytosis, neutrophilia, hypoxia, skin lesions, and altered mental sensorium due to blood poisoning and sepsis shock. Furthermore, blood biochemistry shows elevated inflammation biomarkers like C-reactive protein (CRP) and procalcitonin (PCT). Upon progression to severe sepsis infection or septic shock patient develops hypothermia, oliguria, anuria, acidosis, elevated liver enzymes, severe leukopenia, disseminated vascular coagulation, adult respiratory distress syndrome, hypotension, and shock leading to death.
Diagnosis of Sepsis:
Accurate clinical diagnosis of acute sepsis disease is crucial for effective management of infection progression. A detailed clinical investigation, including patient medical history, signs, and sepsis symptoms, increases the likelihood of accurate diagnosis. More often, sepsis infection requires multiple diagnostic modalities for disease confirmation. In addition, clinical examination for predisposing factors like trauma, surgery, organ transplantation, and previous infection enables determining the source or foci of infection.
Moreover, identification of sepsis infection etiology through microbiological culture and antimicrobial susceptibility testing guide in tailoring specific antimicrobial therapy regimens for infection sepsis treatment.
In addition, haemogram and infection biomarkers such as C-reactive protein (CRP) and procalcitonin (PCT) aid in determining the severity of sepsis and sepsis shock. However, in hospitalized patients, pulse oximetry, complete blood count (CBC), arterial blood gasses analysis, serum electrolytes, liver and kidney function tests, C-reactive protein level, and microbiological examination of blood guarantee accurate diagnostic specificity and identification of causative pathogens.
An Insight into Sepsis and Septic Shock Samples We Offer:
Central BioHub is a global international biospecimen provider specialized in catering human specimens for translational and precision medicine research. Simplifying the tedious biosample procurement process, Central BioHub connects certified global human biobank to biomedical researchers through a most straightforward, open access, and interoperable, user-friendly online marketplace. We supply high-quality human biospecimens that pass rigorous quality control to optimize ultimate precision in the research endpoint.
Accelerating translational, therapeutic, prognostic, and diagnostic research on sepsis, Central BioHub offers you the world’s most extensive human biospecimen inventory comprising thousands of genetically diverse sepsis biospecimens. We provide human serum and plasma samples processed from carefully collected peripheral blood from sepsis patients of different ages, gender, and ethnicities. Blood specimens are precisely examined for sepsis biomarkers like C-reactive protein (CRP), procalcitonin (PCT), bilirubin, creatinine, D-dimer, lactate dehydrogenase, and cryogenically preserved at <-18°C at our partner’s biobanks.
We offer sepsis research samples ranging from small to bulk volumes immediately available for purchase. Valuing our client’s time and patience, every sample request is processed promptly and shipped to your destination swiftly. Our global transport network ensures safe, reliable, speedy delivery of samples to any location.
Online sepsis sample ordering through our portal ensures that you have access to high-quality sepsis biomarker samples with ease. Our online sepsis sample inventory is designed to streamline the PCT and CRP sample ordering process, ensuring that you can order sepsis biospecimens online without any hassle.
Explore advanced search options to procure sepsis samples by clicking Clinical Diagnosis, ICD-10-CM Codes, and Laboratory Parameters.