Autoimmune conditions like Hashimoto's disease and Grave's disease are the main causes of thyroid disorders. In Graves disease, the immune system mistakenly produces antibodies that attack the thyroid and pituitary gland, causing overproduction of thyroid hormones. On the other hand, Hashimoto' thyroiditis is when the immune system destroys healthy thyroid gland cells causing progressive fibrosis that results in reduced synthesis and secretion of thyroid hormones into the bloodstream. However, the exact reason behind this immune system malfunctioning is unclear. Central BioHub offers access to a wide range of human biosamples well maintained at the human biobanks across the globe. Browse our inventory for Graves and Hashimotos disease samples.
Clinical Presentation of Autoimmune Thyroid Disease:
Clinical presentations of Graves’ disease and Hashimoto hypothyroidism are always multifaceted with gradual onset and disease progression.
Graves’ disease Symptoms and Signs: Unintended weight loss, Goitre, muscle weakness, fatigue, hair loss, heat intolerance, profuse sweating, tachycardia, Grave’s ophthalmopathy and behavioral symptoms like anxiety, nervousness, irritability, and insomnia.
Hashimoto’s thyroiditis Symptoms and Signs: Unusual weight gain, enlarged thyroid gland, fatigue, paleness or facial puffiness, dry, dull, thin, and brittle hair, partial alopecia, muscle and joint pain, difficulty in getting pregnant, cold intolerance, irregular or heavy menstruation, bradycardia, and depression.
Insight to the Autoimmune Thyroid Diseases Biospecimens We Offer:
With the most comprehensive research biospecimen inventory, Central BioHub has a proven record of a service history of meeting the biosample needs of global biomedical researchers. Our versatile online marketplace facilitates the quick and reliable acquisition of human biospecimens for research.
We are dedicated to offering precisely annotated, quality-checked Graves' disease and Hashimoto's thyroiditis samples obtained ethically from thyroid patients through customized sampling procedures. Maintaining strict Patient’s anonymity, we provide sample descriptions such as relevant clinical information, and donor demographics like age, gender, ethnicity, BMI, and country of sample origin. Besides, Grave's and Hashimoto's thyroiditis treatment details are also provided. Furthermore, We offer Grave's disease and hashimoto's thyroiditis samples such as human serum and plasma samples processed from whole peripheral blood that are incisively measured for thyroid-stimulating hormone (TSH), triiodothyronine (T3), thyroxine (T4), and thyroglobulin (Tg). Besides, samples are subjected to antibody testings like TSH receptor antibodies (TRAb), antithyroid peroxidase (aTPO / MAK) or thyroid peroxidase antibodies (anti-TPO), and anti-thyroglobulin (aTg /TAK) and are cryogenically preserved at <-18 °C at state-of-the-art biobank. Moreover, our scientific customer experts provide complete assistance to your whole procurement process of thyroid disease biospecimens. Browse our inventory for procuring autoimmune thyroid disease serum and plasma samples online.
Explore advanced search options to procure autoimmune thyroiditis samples by clicking Clinical Diagnosis, ICD-10-CM Codes, and Laboratory Parameters.